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But now scientists at the German Cancer Research Center have found an additional parasite strategy to escape the immune system: They confuse the defense system with sugar. The sugar chains on the coat protein prevent the binding of protective antibodies and thus increase the pathogenic properties of the unicellular pathogens.
Typical mutation in cancer cells stifles immune response The exchange of a single amino acid building block in a metabolic enzyme can lead to cancer. In addition, it can impair the immune system, scientists from the German Cancer Research Center (DKFZ), the University Hospitals in Mannheim and Heidelberg, and the German Cancer Consortium now report.
It thus blocks the body's immune response in the battle against the mutant molecule and also impedes immunotherapy against brain cancer.